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Stem Cell

Stem cells are specialized cells that have the unique ability to develop into different types of cells within the body. They play a crucial role in the growth, repair, and regeneration of tissues and organs. Stem cells are often activated by signaling pathways, which are complex systems of communication within cells that regulate various cellular processes.

Stem cell signaling pathways control the behavior and function of stem cells, including their self-renewal, differentiation, and proliferation. These pathways involve the interaction of various signaling molecules, receptors, and transcription factors that work together to transmit signals and trigger specific cellular responses.

Understanding stem cell signaling pathways is essential for harnessing the potential of stem cells in regenerative medicine, tissue engineering, and disease therapy. By manipulating these pathways, researchers can control the fate and function of stem cells, guiding them towards specific cell types for therapeutic applications.

Overall, stem cell signaling pathways are a critical subcategory of signaling pathways that play a vital role in the regulation of stem cell behavior and hold immense potential for advancing medical treatments and therapies.

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Windorphen, B5977, C17H15ClO3, Wnt inhibitor
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CCT251545, B5979, C23H24ClN5O, Orally bioavailable and potent WNT signaling inhibitor
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SAG

SAG, B5837, C28H28ClN3OS, Hh and Smo agonist
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GSK503, B5833, C31H38N6O2, EZH2 inhibitor
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CHIR 99021 trihydrochloride, B5779, C22H18Cl2N8·3HCl, A glycogen synthase kinase 3 (GSK-3) inhibitor
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Shz 1, B5772, C13H11BrN2O3S, induces phenotypic differentiation
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M 25, B5766, C23H29N3O2, Smoothened (Smo) receptor antagonist
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GSA 10, B5767, C26H30N2O5, Smoothened (Smo) receptor agonist
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CCT 031374 hydrobromide, B5679, C23H19N3O·HBr, inhibits TCF-dependent transcription, blocks BIO-induced β-catenin stabilization
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SMANT hydrochloride, B5674, C16H23BrN2O·HCl, Smoothened (Smo) signaling inhibitor

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