APExBIO Technology LLC

About

ApexBio is a leading provider of high-quality small molecule inhibitors, modulators, and research reagents for drug discovery, chemical biology, and biomedical research. Committed to innovation, reliability, and customer satisfaction, ApexBio offers an extensive catalog of products and services to support scientists, pharmaceutical companies, and academic institutions worldwide. Their dedication to advancing scientific research and drug development has established them as a trusted partner in the life sciences community.

Products

  1. Small Molecule Inhibitors:
    • Kinase Inhibitors: Small molecule inhibitors targeting protein kinases involved in cellular signaling pathways, including receptor tyrosine kinases, serine/threonine kinases, and protein kinase inhibitors.
    • Enzyme Inhibitors: Inhibitors of enzymes involved in various biochemical processes, including proteases, phosphatases, dehydrogenases, and transferases.
    • Ion Channel Modulators: Modulators of ion channels, including voltage-gated ion channels, ligand-gated ion channels, and ion channel blockers.
  2. Modulators and Agonists:
    • GPCR Modulators: Small molecule modulators of G protein-coupled receptors (GPCRs) involved in signal transduction and cellular communication.
    • Nuclear Receptor Agonists/Antagonists: Ligands and modulators of nuclear receptors, including steroid hormone receptors, orphan nuclear receptors, and transcription factors.
  3. Epigenetic Modulators:
    • Histone Deacetylase (HDAC) Inhibitors: Small molecule inhibitors of histone deacetylases involved in epigenetic regulation of gene expression and chromatin remodeling.
    • DNA Methyltransferase (DNMT) Inhibitors: Inhibitors of DNA methyltransferases involved in DNA methylation and epigenetic silencing of gene expression.
  4. Metabolism Modulators:
    • Metabolic Enzyme Inhibitors: Small molecule inhibitors of metabolic enzymes involved in glycolysis, oxidative phosphorylation, fatty acid synthesis, and nucleotide metabolism.
    • Mitochondrial Metabolism Modulators: Modulators of mitochondrial function, including electron transport chain inhibitors, mitochondrial uncouplers, and mitochondrial biogenesis activators.
  5. Cell Signaling Pathway Modulators:
    • MAPK/ERK Pathway Inhibitors: Inhibitors of mitogen-activated protein kinase (MAPK) and extracellular signal-regulated kinase (ERK) signaling pathways involved in cell proliferation, differentiation, and survival.
    • PI3K/Akt/mTOR Pathway Inhibitors: Inhibitors of phosphoinositide 3-kinase (PI3K), protein kinase B (Akt), and mammalian target of rapamycin (mTOR) signaling pathways involved in cell growth, metabolism, and survival.

Services

  1. Custom Synthesis:
    • Custom Compound Synthesis: Custom synthesis of small molecule inhibitors, modulators, and research compounds with specific chemical structures, properties, and purity levels according to customer requirements.
  2. Medicinal Chemistry:
    • Lead Optimization: Medicinal chemistry services for lead optimization and structure-activity relationship (SAR) studies to improve potency, selectivity, and pharmacokinetic properties of drug candidates.
  3. Biological Assay Services:
    • In vitro Assays: Screening and profiling services using biochemical and cell-based assays to evaluate the potency, selectivity, and mechanism of action of small molecule inhibitors and modulators.

Location:
ApexBio is headquartered in Houston, Texas, USA, with distribution centers and partners located worldwide to ensure efficient shipping and support for customers across the globe.

Contact Information:

  • Headquarters Address: 7505 Fannin street, Suite 410, Houston, TX 77054
    33 Pond Ave, Suite 224, Boston, MA 02445
  • Phone: +1 (832) 696-8203
  • Email: info@apexbt.com
  • Website: ApexBio

ApexBio is dedicated to advancing drug discovery and biomedical research by providing high-quality small molecule inhibitors, modulators, and research reagents to the global scientific community. Their commitment to excellence and customer satisfaction makes them a preferred partner for researchers seeking innovative solutions for their research projects.

We are proud to announce that we are the authorized distributor for APExBIO Technology LLC in India. 

For more information or to place an order, feel free to reach out to us. We look forward to serving your research needs with high-quality APExBIO Technology LLC products and services.

To order any products or services, please contact us at:

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