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Chemokines

Chemokines are a subcategory of signaling pathways that play a crucial role in directing the movement of cells in the immune system. These small proteins act as chemoattractants, guiding immune cells to sites of infection, inflammation, and tissue damage. Chemokines are produced by various cell types, including immune cells, endothelial cells, and fibroblasts.

Once released, chemokines bind to specific receptors on the surface of target cells, triggering a series of intracellular signaling events that ultimately lead to cell migration. This migration is essential for the immune response, as it allows immune cells to reach and eliminate pathogens or damaged cells effectively.

In addition to their role in immune responses, chemokines also play a role in other physiological processes, such as tissue development, angiogenesis, and wound healing. Dysregulation of chemokines and their receptors has been implicated in various diseases, including cancer, autoimmune disorders, and inflammatory conditions.

Overall, chemokines are crucial mediators of cell migration and immune responses, highlighting their importance in maintaining homeostasis and defending the body against pathogens and injuries.

Product Search

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MIP-3beta, murine recombinant protein, P1049, N/A, MIP-3β, chemokine, expressed in E.Coli.
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(CXCL12), human recombinant protein, P1042, N/A, SDF-1α (CXCL12), chemokines, expressed in E.Coli, cross-species reactivity.
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SDF-1beta (CXCL12), human recombinant, P1043, N/A, SDF-1β (CXCL12), chemokines, expressed in E.Coli, cross-species reactivity.
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JE (MCP-1), murine recombinant protein, P1034, N/A, JE (MCP-1), chemokine, expressed in E.Coli, active on human cells.

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