Peptides & Proteins

Peptides and proteins are an important subcategory of signaling pathways in living organisms. These signaling molecules play a crucial role in transmitting messages within cells and between cells, coordinating various physiological processes and responses. Peptides are short chains of amino acids, while proteins are larger molecules made up of one or more polypeptide chains.

Peptides and proteins act as signaling molecules by binding to specific receptors on the cell surface or inside the cell. This binding triggers a series of intracellular events that ultimately lead to a cellular response. These molecules are involved in a wide range of signaling pathways, including those regulating cell growth, differentiation, metabolism, and immune responses.

Some well-known examples of peptide and protein signaling molecules include growth factors, cytokines, hormones, and neurotransmitters. Dysregulation of these signaling pathways can lead to various diseases and disorders, making peptides and proteins attractive targets for therapeutic interventions. Researchers continue to study and explore the diverse roles of peptides and proteins in signaling pathways to gain a better understanding of their mechanisms and potential clinical applications.

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Recombinant Rat SCF, P1197, N/A, Stem Cell Factor (SCF) which binds to the c-Kit receptor is produced by fibroblasts and endothelial cells.
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Recombinant Rat G-CSF, P1198, N/A, Granulocyte colony stimulating factor (G-CSF) is a pleiotropic cytokine. It is mainly produced by monocytes and macrophages upon activation by endotoxin, TNF-α and IFN-γ
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Recombinant Rat IL-21, P1194, N/A, Rat IL-21 is produced by CD4+ T cells in response to antigenic stimulation and can regulating immune system cells, for instance cytotoxin T cells and natural killer cells.
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Recombinant Rat IL-10, P1191, N/A, Interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is the charter member of the IL-10 family of α-helical cytokines that also includes IL-19, IL-20, IL-22, IL-24, and IL-26/AK155.
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Recombinant Rat IL-13, P1192, N/A, Interleukin-13 (IL-13) is expressed by the IL13 gene and secreted by many cell types, especially T helper type 2 (Th2) cells.
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Recombinant Rat IL-17A, P1193, N/A, IL-17A, also named CTLA8 and IL17, is belonging to the IL-17 family and is encoded by the IL-17A gene in humans
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Recombinant Rat IL-7, P1189, N/A, Interleukin-7 (IL-7) is encoded by the IL7 gene and secreted by stromal cells in the red marrow and thymus.
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Recombinant Rat IL-9, P1190, N/A, Interleukin-9 (IL-9) is encoded by the IL9 gene and produced by T-cells and specifically by CD4+ helper cells.
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Recombinant Rat IL-1 alpha, P1185, N/A, nterleukin-1 alpha (IL-1α) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells
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Recombinant Rat IL-2, P1186, N/A, IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation

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