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Membrane Transporter

Membrane transporters are proteins that are responsible for moving molecules such as ions, nutrients, and proteins across cell membranes. These transporters play a crucial role in maintaining the homeostasis of cells by regulating the internal environment and communicating with the external environment.

Membrane transporters are a subcategory of signaling pathways as they are involved in transmitting signals between cells and their external environment. They help cells respond to changes in their surroundings, such as changes in nutrient availability or exposure to toxins.

There are several types of membrane transporters, including channels, carriers, and pumps, each with specific functions and mechanisms for transporting molecules across the membrane. Channels allow for passive diffusion of molecules, carriers facilitate the movement of specific molecules, and pumps actively transport molecules against their concentration gradients.

Overall, membrane transporters are essential for cellular function and are crucial for communication between cells and their environment. Understanding the role of membrane transporters in signaling pathways is vital for understanding how cells respond to their surroundings and maintaining cellular homeostasis.

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Estradiol 17-(β-D-Glucuronide) (sodium salt), C3840, C24H31O8·Na, substrate of the multidrug resistance protein 2 (MRP2)
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Barnidipine (hydrochloride), C3727, C27H29N3O6·HCl, calcium-channel blocker
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Eniporide, C3709, C14H16N4O3S, Na+/H+ exchange inhibitor
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Hypophyllanthin, C3610, C24H30O7, P-glycoprotein (P-gp) inhibitor
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Ethyl 3-Aminobenzoate (methanesulfonate), C3619, C9H11NO2·CH4O3S, block the generation of action potentials through voltage-dependent Na+-channels
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2,3-Butanedione-2-monoxime, C3564, C4H7NO2, myosin ATPase inhibitor
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5-(N,N-dimethyl)-Amiloride (hydrochloride), C3505, C8H12ClN7O·HCl, NHE1, NHE2, and NHE3 inhibitor
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Oligomycin B, C3496, C45H72O12, mitochondrial F1FO ATP synthase inhibitor
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Enniatin Complex, C3498, C33H57N3O9 (for B), ionophore
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Zoniporide (hydrochloride), C3480, C17H16N6O·HCl, sodium-hydrogen exchanger isoform-1 (NHE-1) inhibitor

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