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Immunology/Inflammation

Immunology/Inflammation signaling pathways involve a complex network of molecules and interactions that regulate the immune response and inflammatory processes in the body. These pathways play a crucial role in defending the body against pathogens and maintaining tissue homeostasis.

The immune response is initiated by the recognition of pathogens or damage-associated molecular patterns by immune cells, leading to the activation of signaling molecules such as cytokines, chemokines, and growth factors. These signaling molecules then trigger a cascade of events that coordinate the recruitment of immune cells to the site of infection or injury, the activation of these immune cells, and the production of inflammatory mediators to eliminate the threat.

Dysregulation of immunology/inflammation signaling pathways can lead to chronic inflammatory conditions, autoimmune diseases, and increased susceptibility to infections. Understanding these pathways is essential for developing targeted therapies to modulate the immune response and treat a variety of immune-related disorders.

Overall, immunology/inflammation signaling pathways are a crucial subcategory of signaling pathways that govern the immune system’s response to threats and maintain tissue health and integrity.

Product Search

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PS 1145 dihydrochloride, B7683, C17H11ClN4O·2HCl, IκB kinase (IKK) inhibitor
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PD 146176, B7208, C15H11NS, 15-lipoxygenase (15-LOX) inhibitor
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Withaferin A, B7199, C28H38O6, Prevents NF-κB activation by inhibiting activation of IKKβ
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RWJ 21757, B7159, C13H17N5O6, Toll-like receptor 7 (TLR7) agonist
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Cardamonin, B7085, C16H14O4, NF-κB inhibitor
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Ro 106-9920, B6853, C10H7N5OS, Inhibitor of NF-κB activation
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MK 886, B6684, C27H34ClNO2S, A FLAP and PPARα inhibitor, capable of inhibiting leukotriene biosynthesis and inducing apoptosis
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BW-B 70C, B6680, C17H17FN2O3, 5-Lipoxygenase inhibitor,potent and selective
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Pyrrolidinedithiocarbamate ammonium, B6422, C5H12N2S2, NF-κB inhibitor
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2-TEDC, B6391, C16H13NO4S, 5-, 12-, and 15-lipoxygenase inhibitor

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