Cell Cyde/Checkpoint

The cell cycle is a tightly regulated process responsible for growth and division of cells. Cell cycle checkpoints are key regulatory mechanisms that ensure each step of the cell cycle is completed accurately before progressing to the next phase. These checkpoints monitor DNA integrity, cell size, and environmental conditions to prevent errors in cell division that could lead to genetic abnormalities and diseases such as cancer.

Cell cycle checkpoints are activated by signaling pathways that respond to external signals and internal cues to coordinate the progression of the cell cycle. These pathways involve a complex network of proteins and molecules that communicate information about the cell’s status and trigger the appropriate responses to maintain genomic stability.

Dysregulation of cell cycle checkpoints can disrupt the normal progression of the cell cycle, leading to uncontrolled cell growth and proliferation. Understanding the molecular mechanisms of cell cycle checkpoints and the signaling pathways that regulate them is crucial for developing targeted therapies to treat diseases caused by aberrant cell cycle regulation. Researchers continue to explore these pathways to uncover potential therapeutic targets for cancer and other diseases characterized by abnormal cell division.