rna isolation

RNA purification made simple. Discover industry-leading RNA purification technology at a fraction of the cost.

Direct-zol RNA Kits


RNA purification kits that provide purification of up to 100 µg (per prep) of high-quality RNA directly from samples in TRIzol or Tri Reagent in 7 minutes. Get a free RNA purification kits sample with free shipping.

Quick-RNA Kits


The Quick-RNA kits are RNA isolation kits that provide easy and reliable isolation of DNA-free RNA from most samples in just 10 minutes. Get a free sample today with free shipping.

Quick-RNA Viral Kits


The Quick- RNA Viral Kits are viral RNA purification kits that provide for rapid isolation of high-quality viral RNA from a wide range of biological sources.

Quick-RNA Whole Blood


Isolate RNA and small/miRNA from whole blood.

Quick-RNA FFPE Miniprep


Isolate RNA and small/miRNA from FFPE tissue.

ZymoBIOMICS RNA Miniprep Kit


Purification of microbial RNA for microbiome or metagenome analyses

Quick-RNA Fungal/Bacterial Kit


Easily and quickly isolate total RNA from tough-to-lyse fungi and bacteria.

Quick-RNA Tissue/Insect Kit


Isolate RNA from tough-to-lyse tissue and insects

Quick-RNA Fecal/Soil Microbe Microprep Kit


The Quick-RNA Fecal/Soil Microbe Microprep Kit is an affordable fecal and soil RNA extraction kit designed for fast, easy isolation of total RNA including small RNAs from soil, sludge, sediment and fecal samples.

Quick-RNA Plant Kit


Isolate inhibitor-free RNA from plant and seed samples.

Quick-cfRNA Serum & Plasma Kit


Isolate cell-free RNA from biological fluid samples

ZR Urine RNA Isolation Kit

R1038, R1039

Isolate RNA from up to 30 ml of urine.


The quality of RNA obtained from biological samples or reaction mixtures is of critical importance to the success of downstream applications including real-time quantitative PCR, reverse transcription PCR, microarrays, Northern blot analysis, nuclease protection assays, RNA mapping, in vitro translation, cDNA library construction, etc.

Thus, it is essential that the methods of extracting, purifying or isolating RNA from different types of cells and tissues produce RNA of sufficient yield and structural integrity. With this in mind, the scientists at Zymo Research have developed a range of RNA extraction, purification and isolation kits designed for the efficient recovery of high-quality RNA from a diversity of sources.

RNA Clean-up & Concentration

Purification of RNA from different types of cells and tissues has been difficult in the past, however high-quality RNA is essential for the success of downstream applications such as microarrays, RNA transfection, denaturing-gel electrophoresis, Northern blotting and RT-PCR. Zymo Research Corporation has used their state of the art ‘Fast-Spin’ column technology to produce the RNA Clean & Concentrator kit. This kit recovers a highly concentrated RNA, while still ensuring the structural integrity of the product.

Total RNA Purification

Zymo Research offers an assortment of products that allow for the simple, rapid, and efficient isolation of total RNA from a variety of biological sources including fresh, frozen, or paraffin-embedded tissues, cultured cells, buccal cells, whole blood, plasma, serum, urine, yeast, or RNA viruses. Like our RNA clean-up kits, all of the RNA isolation kits feature Fast-Spin column technology for highly concentrated RNA that is well suited for applications like microarrays, denaturing-gel electrophoresis, Northern blotting, and RT-PCR. The versatile solution for total RNA purification, Quick-RNA kits are available in Micro-, Mini-, Midi- and 96-well format. Additionally, the ZR RNA MicroPrep™ and ZR RNA MiniPrep™ kits are capable of isolating RNA species as small as 17 nt. Each kit has been optimized for a particular application with specialized, nuclease-free components that ensure: 1) maximum levels of membrane solubilization and cellular disruption, 2) total inhibition of nuclease activity, 3) complete deproteinization of the sample, 4) efficient isolation and concentration of the RNA, 5) stabilization and safe storage of the RNA.

RNA Molecular Weight Marker

Agarose and polyacrylamide gel electrophoresis are two common techniques for determining the size, purity, and sequence identity (e.g., Northern and Southern blotting procedures) of nucleic acids. Nucleic acids can be visualized in gels using fluorescent stains (e.g. ethidium bromide) or by silver staining. RNA size markers (or ladders) are necessary to help identify unknown nucleic acids in gel-based procedures. The ZR small-RNA™ Ladder is ideal for identifying small RNAs (i.e., siRNAs and miRNAs) from 17 – 29 bases in size.