Human Transforming Growth Factors Β2, TGFB2 ELISA Kit
Product Summary
• Size: 48T,96T
• Sensitivity: 3.53ng/L
• Detection range: 7-1500ng/L
• Reactive with: Human
Product Details
Product Specifications |
|
---|---|
Full Product Name: |
Transforming Growth Factors beta2 |
Catalog No.: |
BL0067EH |
Size: |
48T,96T |
Detaction Range: |
7-1500ng/L |
Sensitivity: |
3.53ng/L |
Sample Type: |
Serum, plasma, cell culture supernates |
Assay Type: |
Sandwich |
Species: |
Human |
Storage: |
2-8ºC |
Assay Time: |
1h 30m |
Background: |
Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated Peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. [Latency-associated Peptide]: Required to maintain the Transforming growth factor beta-2 (TGF-beta-2) chain in a latent state during storage in extracellular matrix (By similarity). Associates non-covalently with TGF-beta-2 and regulates its activation via interaction with 'milieu molecules', such as LTBP1 and LRRC32/GARP, that control activation of TGF-beta-2 (By similarity). Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (PubMed: 22772371, PubMed: 22772368). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated Peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains remain non-covalently linked rendering TGF-beta-2 inactive during storage in extracellular matrix (By similarity). At the same time, LAP chain interacts with 'milieu molecules', such as LTBP1 and LRRC32/GARP, that control activation of TGF-beta-2 and maintain it in a latent state during storage in extracellular milieus (By similarity). Once activated following release of LAP, TGF-beta-2 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal (By similarity). |
UniProt: |
|
MASS(Da): |
47,748 |
GeneID: |
7042 |
Synonyms: |
Cetermin;Glioblastoma-derived T-cell suppressor factor;G-TSF;LAP;Latency-associated Peptide;TGF B2;TGF beta2;TGFB 2;TGFB2;TGF-beta-2;Transforming growth factor beta-2;Transforming growth factor beta-2 proprotein |
Gene Names: |
TGFB2 |
Research Area: |
Signal Transduction |
Target Protein: |
TGFB2 |
*For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Components
Components | Quantity |
Pre-coated ELISA Plate | 12 * 8 well strips x1 |
Standard solution | 0.5ml x1 |
Standard diluent | 3ml x1 |
Streptavidin-HRP | 6ml x1 |
Stop solution | 6ml x1 |
Substrate solution A | 6ml x1 |
Substrate solution B | 6ml x1 |
Wash buffer concentrate | (25x) 20ml x1 |
Biotinylated antibody | 1ml x1 |
Documents
Technical Guide
Technical Guide: Human Transforming Growth Factors Β2, TGFB2 ELISA KitSafety Data Sheets (SDS)
MSDS: Human Transforming Growth Factors Β2, TGFB2 ELISA KitReferences
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