Full Product Name:

Protein S100-B

Catalog No.:

BL3669EH

Size:

48T,96T

Detaction Range:

0.5-300ng/L

Sensitivity:

0.22ng/L

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Human

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

UniProt:

P04271

MASS（Da）:

10,713

GeneID:

6285

Synonyms:

Protein S100-B;S100 calcium-binding protein B;S-100 protein beta chain;S-100 protein subunit beta;S100B

Gene Names:

S100B

Research Area:

Signal Transduction

Target Protein:

S100B