Full Product Name:

Platelet Basic Protein

Catalog No.:

BL1135EH

Size:

48T,96T

Detaction Range:

0.1-40ng/mL

Sensitivity:

0.043ng/mL

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Human

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.

UniProt:

P02775

MASS（Da）:

13,894

GeneID:

5473

Synonyms:

Beta-TG;Beta-thromboglobulin;Connective tissue-activating Peptide III;Connective tissue-activating Peptide III(1-81;CTAP-III;CTAP-III(1-81;C-X-C motif chemokine 7;LA-PF4;LDGF;Leukocyte-derived growth factor;Low-affinity platelet factor IV;Macrophage-derived growth factor;MDGF;NAP-2;NAP-2(1-63;NAP-2(1-66;NAP-2(73;NAP-2(74;Neutrophil-activating Peptide 2;Neutrophil-activating Peptide 2(1-63;Neutrophil-activating Peptide 2(1-66;Neutrophil-activating Peptide 2(73;Neutrophil-activating Peptide 2(74;PBP;Platelet basic protein;PPBP;Small-inducible cytokine B7;TC-1;TC-2

Gene Names:

PPBP

Research Area:

Immunology

Target Protein:

PPBP