Full Product Name:

Peroxisome Proliferators Activator Receptors Alpha

Catalog No.:

BL1450EH

Size:

48T,96T

Detaction Range:

30-9000ng/L

Sensitivity:

14.22ng/L

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Human

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

UniProt:

Q07869

MASS（Da）:

52,225

GeneID:

5465

Synonyms:

Nuclear receptor subfamily 1 group C member 1;Peroxisome proliferator-activated receptor alpha;PPARA;PPAR-alpha

Gene Names:

PPARA

Research Area:

Metabolism

Target Protein:

PPARA