Human Parathyroid Hormone-like Protein, PLP ELISA Kit
Product Summary
• Size: 48T,96T
• Sensitivity: 0.022pmol/L
• Detection range: 0.05-10pmol/L
• Reactive with: Human
Product Details
Product Specifications |
|
---|---|
Full Product Name: |
Parathyroid Hormone-Like Protein |
Catalog No.: |
BL0034EH |
Size: |
48T,96T |
Detaction Range: |
0.05-10pmol/L |
Sensitivity: |
0.022pmol/L |
Sample Type: |
Serum, plasma, cell culture supernates |
Assay Type: |
Sandwich |
Species: |
Human |
Storage: |
2-8ºC |
Assay Time: |
1h 30m |
Background: |
Neuroendocrine Peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath (By similarity). Promotes colon cancer cell migration and invasion in an integrin alpha-6/beta-1-dependent manner through activation of Rac1. Osteostatin is a potent inhibitor of osteoclastic bone resorption. |
UniProt: |
|
MASS(Da): |
20,194 |
GeneID: |
5744 |
Synonyms: |
Osteostatin;Parathyroid hormone-like protein;Parathyroid hormone-related protein;PLP;PTHLH;PTHrP;PTH-rP;PTHrP[107-139];PTHrP[1-36;PTHrP[38-94 |
Gene Names: |
PTHLH |
Research Area: |
Signal Transduction |
Target Protein: |
PTHLH |
*For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Components
Components | Quantity |
Pre-coated ELISA Plate | 12 * 8 well strips x1 |
Standard solution | 0.5ml x1 |
Standard diluent | 3ml x1 |
Streptavidin-HRP | 6ml x1 |
Stop solution | 6ml x1 |
Substrate solution A | 6ml x1 |
Substrate solution B | 6ml x1 |
Wash buffer concentrate | (25x) 20ml x1 |
Biotinylated antibody | 1ml x1 |
Documents
Technical Guide
Technical Guide: Human Parathyroid Hormone-like Protein, PLP ELISA KitSafety Data Sheets (SDS)
MSDS: Human Parathyroid Hormone-like Protein, PLP ELISA KitReferences
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