Human Ninein/Gsk3B Interacting Protein, NIN ELISA Kit
Product Summary
• Size: 48T,96T
• Sensitivity: 0.05ng/ml
• Detection range: 0.1-30ng/ml
• Reactive with: Human
Product Details
Product Specifications |
|
---|---|
Full Product Name: |
Ninein/Gsk3B Interacting Protein |
Catalog No.: |
BL3201EH |
Size: |
48T,96T |
Detaction Range: |
0.1-30ng/ml |
Sensitivity: |
0.05ng/ml |
Sample Type: |
Serum, plasma, cell culture supernates |
Assay Type: |
Sandwich |
Species: |
Human |
Storage: |
2-8ºC |
Assay Time: |
1h 30m |
Background: |
A-kinase anchoring protein for GSK3B and PKA that regulates or facilitates their kinase activity towards their targets (PubMed: 27484798, PubMed: 25920809, PubMed: 16981698). The ternary complex enhances Wnt-induced signaling by facilitating the GSK3B- and PKA-induced phosphorylation of beta-catenin leading to beta-catenin degradation and stabilization respectively (PubMed: 27484798, PubMed: 16981698). Upon cAMP activation, the ternary complex contributes to neuroprotection against oxidative stress-induced apoptosis by facilitating the PKA-induced phosphorylation of DML1 and PKA-induced inactivation of GSK3B (PubMed: 25920809). During neurite outgrowth promotes neuron proliferation; while increases beta-catenin-induced transcriptional activity through GSK3B kinase activity inhibition, reduces N-cadherin level to promote cell cycle progression (PubMed: 19830702). |
UniProt: |
|
MASS(Da): |
15,648 |
GeneID: |
51527 |
Synonyms: |
GSK3beta interaction protein;GSK3B-interacting protein;GSKIP |
Gene Names: |
GSKIP |
Research Area: |
Cell Biology |
Target Protein: |
GSKIP |
*For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Components
Components | Quantity |
Pre-coated ELISA Plate | 12 * 8 well strips x1 |
Standard solution | 0.5ml x1 |
Standard diluent | 3ml x1 |
Streptavidin-HRP | 6ml x1 |
Stop solution | 6ml x1 |
Substrate solution A | 6ml x1 |
Substrate solution B | 6ml x1 |
Wash buffer concentrate | (25x) 20ml x1 |
Biotinylated antibody | 1ml x1 |
Documents
Technical Guide
Technical Guide: Human Ninein/Gsk3B Interacting Protein, NIN ELISA KitSafety Data Sheets (SDS)
MSDS: Human Ninein/Gsk3B Interacting Protein, NIN ELISA KitReferences
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