Full Product Name:

Mucin-1

Catalog No.:

BL1939EH

Size:

48T,96T

Detaction Range:

0.05-15ng/ml

Sensitivity:

0.024ng/ml

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Human

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

UniProt:

P15941

MASS（Da）:

122,102

GeneID:

4582

Synonyms:

Breast carcinoma-associated antigen DF3;CA 15-3;Cancer antigen 15-3;Carcinoma-associated mucin;CD antigen CD227;EMA;Episialin;H23AG;KL-6;Krebs von den Lungen-6;MUC 1;MUC1;MUC-1;MUC1-alpha;MUC1-beta;MUC1-CT;MUC1-NT;Mucin-1;Mucin-1 subunit alpha;Mucin-1 subunit beta;Peanut-reactive urinary mucin;PEM;PEMT;Polymorphic epithelial mucin;PUM;Tumor-associated epithelial membrane antigen;Tumor-associated mucin

Gene Names:

MUC1

Research Area:

Cancer

Target Protein:

MUC1