Human Interleukin 33, IL-33 ELISA Kit
Product Summary
• Size: 48T,96T
• Sensitivity: 5.36ng/L
• Detection range: 10-2000ng/L
• Reactive with: Human
Product Details
Product Specifications |
|
---|---|
Full Product Name: |
Interleukin 33 |
Catalog No.: |
BL0044EH |
Size: |
48T,96T |
Detaction Range: |
10-2000ng/L |
Sensitivity: |
5.36ng/L |
Sample Type: |
Serum, plasma, cell culture supernates |
Assay Type: |
Sandwich |
Species: |
Human |
Storage: |
2-8ºC |
Assay Time: |
1h 30m |
Background: |
Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed: 16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury (PubMed: 17853410, PubMed: 18836528). In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets (PubMed: 21734074). This form is rapidely lost upon angiogenic or proinflammatory activation (PubMed: 18787100). |
UniProt: |
|
MASS(Da): |
30,759 |
GeneID: |
90865 |
Synonyms: |
109-270;95-270;99-270;IL 33;IL-1F11;IL33;IL-33;Interleukin-1 family member 11;Interleukin-33;NF-HEV;Nuclear factor from high endothelial venules |
Gene Names: |
IL33 |
Research Area: |
Cardiovascular; Immunology |
Target Protein: |
IL33 |
*For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Components
Components | Quantity |
Pre-coated ELISA Plate | 12 * 8 well strips x1 |
Standard solution | 0.5ml x1 |
Standard diluent | 3ml x1 |
Streptavidin-HRP | 6ml x1 |
Stop solution | 6ml x1 |
Substrate solution A | 6ml x1 |
Substrate solution B | 6ml x1 |
Wash buffer concentrate | (25x) 20ml x1 |
Biotinylated antibody | 1ml x1 |
Documents
Technical Guide
Technical Guide: Human Interleukin 33, IL-33 ELISA KitSafety Data Sheets (SDS)
MSDS: Human Interleukin 33, IL-33 ELISA KitReferences
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