Full Product Name:

Interleukin 18

Catalog No.:

BL0147EH

Size:

48T,96T

Detaction Range:

0.5-100ng/L

Sensitivity:

0.2ng/L

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Human

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators (PubMed: 14528293, PubMed: 25500532). Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable) (PubMed: 10653850).

UniProt:

Q14116

MASS（Da）:

22,326

GeneID:

3606

Synonyms:

Iboctadekin;IFN-gamma-inducing factor;IL 18;IL-1 gamma;IL18;IL-18;Interferon gamma-inducing factor;Interleukin-1 gamma;Interleukin-18;

Gene Names:

IL18

Research Area:

Immunology

Target Protein:

IL18