Human Glucagon-like Peptide 1, GLP1 ELISA Kit
Product Summary
• Size: 48T,96T
• Sensitivity: 1.27pmol/L
• Detection range: 2-180pmol/L
• Reactive with: Human
Product Details
Product Specifications |
|
---|---|
Full Product Name: |
Glucagon-Like Peptide 1 |
Catalog No.: |
BL0022EH |
Size: |
48T,96T |
Detaction Range: |
2-180pmol/L |
Sensitivity: |
1.27pmol/L |
Sample Type: |
Serum, plasma, cell culture supernates |
Assay Type: |
Sandwich |
Species: |
Human |
Storage: |
2-8ºC |
Assay Time: |
1h 30m |
Background: |
[Glucagon]: Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. [Glucagon-like Peptide 1]: Potent stimulator of glucose-dependent insulin release. Also stimulates insulin release in response to IL6 (PubMed: 22037645). Plays important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Has growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis (Probable). [Glucagon-like Peptide 2]: Stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability. [Oxyntomodulin]: Significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness. [Glicentin]: May modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life. |
UniProt: |
|
MASS(Da): |
20909 |
GeneID: |
2641 |
Synonyms: |
GCG;Glicentin-related polypeptide;GLP-1;GLP-1(7-36);GLP-1(7-37);GLP-2;Glucagon;Glucagon-like Peptide 1;Glucagon-like Peptide 1(7-36);Glucagon-like Peptide 1(7-37);Glucagon-like Peptide 2;GRPP;Incretin hormone;OXM;OXY;Oxyntomodulin;Pro-glucagon Glicentin |
Gene Names: |
GCG |
Research Area: |
Metabolism |
Target Protein: |
GCG |
*For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Components
Components | Quantity |
Pre-coated ELISA Plate | 12 * 8 well strips x1 |
Standard solution | 0.5ml x1 |
Standard diluent | 3ml x1 |
Streptavidin-HRP | 6ml x1 |
Stop solution | 6ml x1 |
Substrate solution A | 6ml x1 |
Substrate solution B | 6ml x1 |
Wash buffer concentrate | (25x) 20ml x1 |
Biotinylated antibody | 1ml x1 |
Documents
Technical Guide
Technical Guide: Human Glucagon-like Peptide 1, GLP1 ELISA KitSafety Data Sheets (SDS)
MSDS: Human Glucagon-like Peptide 1, GLP1 ELISA KitReferences
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