Full Product Name:

C-C Motif Chemokine 4

Catalog No.:

BL5008EH

Size:

48T,96T

Detaction Range:

10-2000ng/L

Sensitivity:

5.12ng/L

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Human

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

UniProt:

P13236

MASS（Da）:

10,212

GeneID:

3883726351

Synonyms:

ACT-2;C-C motif chemokine 4;CCL 4;CCL4;G-26 T-lymphocyte-secreted protein;HC21;LAG-1;Lymphocyte activation gene 1 protein;Macrophage inflammatory protein 1-beta;MIP-1-beta;MIP-1-beta(1-69;MIP-1-beta(3-69;PAT 744;Protein H400;SIS-gamma;Small-inducible cytokine A4;T-cell activation protein 2

Gene Names:

CCL4

Research Area:

Immunology

Target Protein:

CCL4