Full Product Name:

Bone Morphogenetic Protein Receptor 2

Catalog No.:

BL1563EH

Size:

48T,96T

Detaction Range:

3-900ng/L

Sensitivity:

1.64ng/L

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Human

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

UniProt:

Q13873

MASS（Da）:

115,201

GeneID:

659

Synonyms:

BMP type II receptor;BMP type-2 receptor;BMPR 2;BMPR2;BMPR-2;BMPR-II;Bone morphogenetic protein receptor type II;Bone morphogenetic protein receptor type-2

Gene Names:

BMPR2

Research Area:

Cardiovascular

Target Protein:

BMPR2