Full Product Name:

Bone Morphogenetic Protein 2

Catalog No.:

BL1989EH

Size:

48T,96T

Detaction Range:

0.05-15ng/ml

Sensitivity:

0.01ng/ml

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Human

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Induces cartilage and bone formation (PubMed: 3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed: 24362451).

UniProt:

P12643

MASS（Da）:

44,702

GeneID:

650

Synonyms:

BMP 2;BMP2;BMP-2;BMP-2A;Bone morphogenetic protein 2;Bone morphogenetic protein 2A

Gene Names:

BMP2

Research Area:

Signal Transduction

Target Protein:

BMP2