Human Annexin A1, ANXA1 ELISA Kit
Product Summary
• Size: 48T,96T
• Sensitivity: 0.18ng/ml
• Detection range: 0.3-90ng/ml
• Reactive with: Human
Product Details
Product Specifications |
|
---|---|
Full Product Name: |
Annexin A1 |
Catalog No.: |
BL3288EH |
Size: |
48T,96T |
Detaction Range: |
0.3-90ng/ml |
Sensitivity: |
0.18ng/ml |
Sample Type: |
Serum, plasma, cell culture supernates |
Assay Type: |
Sandwich |
Species: |
Human |
Storage: |
2-8ºC |
Assay Time: |
1h 30m |
Background: |
Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity (PubMed: 8425544). Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response (By similarity). Promotes resolution of inflammation and wound healing (PubMed: 25664854). Functions at least in part by activating the formyl Peptide receptors and downstream signaling cascades (PubMed: 15187149, PubMed: 25664854). Promotes chemotaxis of granulocytes and monocytes via activation of the formyl Peptide receptors (PubMed: 15187149). Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells (PubMed: 17008549). Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells (PubMed: 17008549). Has no effect on unstimulated T cells (PubMed: 17008549). Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration (PubMed: 15187149). Negatively regulates hormone exocytosis via activation of the formyl Peptide receptors and reorganization of the actin cytoskeleton (PubMed: 19625660). Has high affinity for Ca(2+) and can bind up to eight Ca(2+) ions (By similarity). Displays Ca(2+)-dependent binding to phospholipid membranes (PubMed: 2532504, PubMed: 8557678). Plays a role in the formation of phagocytic cups and phagosomes. Plays a role in phagocytosis by mediating the Ca(2+)-dependent interaction between phagosomes and the actin cytoskeleton (By similarity). |
UniProt: |
|
MASS(Da): |
38,714 |
GeneID: |
301 |
Synonyms: |
Annexin A1;Annexin I;Annexin-1;ANXA 1;ANXA1;Calpactin II;Calpactin-2;Chromobindin-9;Lipocortin I;p35;Phospholipase A2 inhibitory protein |
Gene Names: |
ANXA1 |
Research Area: |
Signal Transduction |
Target Protein: |
ANXA1 |
*For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Components
Components | Quantity |
Pre-coated ELISA Plate | 12 * 8 well strips x1 |
Standard solution | 0.5ml x1 |
Standard diluent | 3ml x1 |
Streptavidin-HRP | 6ml x1 |
Stop solution | 6ml x1 |
Substrate solution A | 6ml x1 |
Substrate solution B | 6ml x1 |
Wash buffer concentrate | (25x) 20ml x1 |
Biotinylated antibody | 1ml x1 |
Documents
Technical Guide
Technical Guide: Human Annexin A1, ANXA1 ELISA KitSafety Data Sheets (SDS)
MSDS: Human Annexin A1, ANXA1 ELISA KitReferences
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