Full Product Name:

Toll-Like Receptor 2

Catalog No.:

BL0422E

Size:

48T,96T

Detaction Range:

5-1000ng/ml

Sensitivity:

2.75ng/ml

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Bovine

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides (By similarity).

UniProt:

Q95LA9

MASS（Da）:

90,205

GeneID:

281534

Synonyms:

CD antigen CD282;CD282;TIL4;TLR 2;TLR2;Toll like receptor 2;Toll/interleukin 1 receptor like 4;Toll-like receptor 2

Gene Names:

TLR2

Research Area:

Immunology; Microbiology; Signal Transduction; Cardiovascular

Target Protein:

TLR2