Bovine Smarcc1 ELISA Kit
Product Summary
• Size: 48T,96T
• Sensitivity: 0.023ng/ml
• Detection range: 0.05-10ng/ml
• Reactive with: Bovine
Product Details
Product Specifications |
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Full Product Name: |
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 |
Catalog No.: |
BL0273E |
Size: |
48T,96T |
Detaction Range: |
0.05-10ng/ml |
Sensitivity: |
0.023ng/ml |
Sample Type: |
Serum, plasma, cell culture supernates |
Assay Type: |
Sandwich |
Species: |
Bovine |
Storage: |
2-8ºC |
Assay Time: |
1h 30m |
Background: |
Core component of the BAF (SWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric structures, termed altosomes, each composed of 2 histones octamers. Stimulates in vitro the remodeling activity of SMARCA4/BRG1/BAF190A. Plays a key role in cell-cycle control and causes cell cycle arrest in G0/G1. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). |
UniProt: |
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MASS(Da): |
44,111 |
GeneID: |
537412 |
Synonyms: |
BAF47;BRG1-associated factor 47;SMARCC1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 |
Gene Names: |
SMARCB1 |
Research Area: |
Others |
Target Protein: |
SMARCC1 |
*For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Components
Components | Quantity |
Pre-coated ELISA Plate | 12 * 8 well strips x1 |
Standard solution | 0.5ml x1 |
Standard diluent | 3ml x1 |
Streptavidin-HRP | 6ml x1 |
Stop solution | 6ml x1 |
Substrate solution A | 6ml x1 |
Substrate solution B | 6ml x1 |
Wash buffer concentrate | (25x) 20ml x1 |
Biotinylated antibody | 1ml x1 |
Documents
Technical Guide
Technical Guide: Bovine Smarcc1 ELISA KitSafety Data Sheets (SDS)
MSDS: Bovine Smarcc1 ELISA KitReferences
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