Full Product Name:

Plasminogen Activator Inhibitor 1

Catalog No.:

BL0115E

Size:

48T,96T

Detaction Range:

0.2-60ng/ml

Sensitivity:

0.08ng/ml

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Bovine

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence (By similarity). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity).

UniProt:

P13909

MASS（Da）:

45,371

GeneID:

281375

Synonyms:

Endothelial plasminogen activator inhibitor;PAI;PAI-1;Plasminogen activator inhibitor 1;Serpin E1;SERPINE 1;SERPINE1

Gene Names:

SERPINE1

Research Area:

Cardiovascular; Cancer; Cell Biology

Target Protein:

SERPINE1