Bovine Peptidoglycan Recognition Protein 1, PGLYRP1 ELISA Kit
Product Summary
• Size: 48T,96T
• Sensitivity: 0.091ng/ml
• Detection range: 0.2-60ng/ml
• Reactive with: Bovine
Product Details
Product Specifications |
|
---|---|
Full Product Name: |
Peptidoglycan Recognition Protein 1 |
Catalog No.: |
BL2303E |
Size: |
48T,96T |
Detaction Range: |
0.2-60ng/ml |
Sensitivity: |
0.091ng/ml |
Sample Type: |
Serum, plasma, cell culture supernates |
Assay Type: |
Sandwich |
Species: |
Bovine |
Storage: |
2-8ºC |
Assay Time: |
1h 30m |
Background: |
Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems. Acts as a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria and thus provides bactericidal activity (PubMed: 11880375, PubMed: 16394004). Forms an equimolar complex with heat shock protein HSPA1A and induces programmed cell death through apoptosis and necroptosis in tumor cell lines by activating the TNFR1 receptor on the target cell membrane. In addition, acts in complex with the Ca(2+)-binding protein S100A4 as a chemoattractant able to induce lymphocyte movement. Mechanistically, this complex acts as a ligand of the chemotactic receptors CCR5 and CXCR3 which are present on the cells of the immune system. Promotes also the activation of lymphocytes that become able to kill virus-infected cells as well as tumor cells by modulating the spectrum of their target-cell specificity. Induction of cytotoxicity on monocyte surface requires interaction with TREM1 receptor (By similarity). |
UniProt: |
|
MASS(Da): |
21,063 |
GeneID: |
282305 |
Synonyms: |
OBP;Oligosaccharide-binding protein;Peptidoglycan recognition protein 1;Peptidoglycan recognition protein short;PGLYRP 1;PGLYRP1;PGRP-S |
Gene Names: |
PGLYRP1 |
Research Area: |
Others |
Target Protein: |
PGLYRP1 |
*For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Components
Components | Quantity |
Pre-coated ELISA Plate | 12 * 8 well strips x1 |
Standard solution | 0.5ml x1 |
Standard diluent | 3ml x1 |
Streptavidin-HRP | 6ml x1 |
Stop solution | 6ml x1 |
Substrate solution A | 6ml x1 |
Substrate solution B | 6ml x1 |
Wash buffer concentrate | (25x) 20ml x1 |
Biotinylated antibody | 1ml x1 |
Documents
Technical Guide
Technical Guide: Bovine Peptidoglycan Recognition Protein 1, PGLYRP1 ELISA KitSafety Data Sheets (SDS)
MSDS: Bovine Peptidoglycan Recognition Protein 1, PGLYRP1 ELISA KitReferences
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