Full Product Name:

Legumain

Catalog No.:

BL0328E

Size:

48T,96T

Detaction Range:

5-1500ng/L

Sensitivity:

2.63ng/L

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Bovine

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). Required for normal lysosomal protein degradation in renal proximal tubules. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.

UniProt:

Q95M12

MASS（Da）:

49,284

GeneID:

281281

Synonyms:

Asparaginyl endopeptidase;Legumain;LGMN;Protease, cysteine 1

Gene Names:

LGMN

Research Area:

Others

Target Protein:

LGMN