Full Product Name:

Hydroxymethylglutaryl-CoA lyase

Catalog No.:

BL2217E

Size:

48T,96T

Detaction Range:

15-3000ng/L

Sensitivity:

7.26ng/L

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Bovine

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

UniProt:

Q29448

MASS（Da）:

34,168

GeneID:

317658

Synonyms:

3-hydroxy-3-methylglutarate-CoA lyase;HL;HMGCL;HMG-CoA lyase;Hydroxymethylglutaryl-CoA lyase, mitochondrial

Gene Names:

HMGCL

Research Area:

Others

Target Protein:

HMGCL