Full Product Name:

Cystatin C

Catalog No.:

BL2053E

Size:

48T,96T

Detaction Range:

0.05-15mg/L

Sensitivity:

0.02mg/L

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Bovine

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin, or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.

UniProt:

P01035

MASS（Da）:

16,265

GeneID:

281102

Synonyms:

Colostrum thiol proteinase inhibitor;Cys-C;Cystatin-3;Cystatin-C

Gene Names:

CST3

Research Area:

Cardiovascular

Target Protein:

Cystatin-3