Full Product Name:

Angiopoietin 2

Catalog No.:

BL0044E

Size:

96T, 48T

Detaction Range:

10-3000ng/L

Sensitivity:

5.19ng/L

Sample Type:

Serum, plasma, cell culture supernates

Assay Type:

Sandwich

Species:

Bovine

Storage:

2-8ºC

Assay Time:

1h 30m

Background:

Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating angiogenic signals mediated by ANGPT1. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (By similarity).

UniProt:

O77802

MASS（Da）:

56,539

GeneID:

282141

Synonyms:

ANG 2;ANG2;ANG-2;Angiopoietin-2

Gene Names:

ANG-2

Research Area:

Cardiovascular

Target Protein:

ANG-2