SCNN1B(Thr615) Polyclonal Antibody
- Size: 100ul
- Application: WB, ELISA, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
- Reactivity: Human
- Predicted Reactivity: Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit, Guinea Pig
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Datasheet
Tech Support
IMAGES
Lane 1: Siha cell lysates; Lane 2: A549 cell lysates probed with SCNN1B(Thr615) Polyclonal Antibody, Unconjugated (bs-5701R) at 1:300 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.
PRODUCT DETAILS
SPECIFICATIONS |
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|---|---|
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PRODUCT NAME |
SCNN1B(Thr615) Polyclonal Antibody |
|
CONJUGATION |
Unconjugated |
|
HOST |
Rabbit |
| SOURCE |
KLH conjugated synthetic phosphopeptide derived from human SCNN1B around the phosphorylation site of Thr615 |
| IMMUNOGEN RANGE |
|
| CLONALITY |
Polyclonal |
| ISOTYPE |
IgG |
| CONCENTRATION |
1ug/ul |
| PURIFICATION |
Purified by Protein A. |
| STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
| STORAGE CONDITION |
Store at -20°C for 12 months.. |
TARGET |
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|---|---|
| GENE ID |
|
| SUBCELLULAR LOCATION |
Cell membrane |
| SYNONYMS |
BESC1; ENaCb; SCNEB; ENaCbeta; Amiloride-sensitive sodium channel subunit beta; Beta-NaCH; Epithelial Na(+) channel subunit beta; Beta-ENaC; Nonvoltage-gated sodium channel 1 subunit beta; SCNN1B |
| BACKGROUND |
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. |
| APPLICATION DILUTION |
WB(1:300-1000), ELISA(1:500-1000), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200) |
