LMAN1 Monoclonal Antibody
- Size: 100ul
- Application: WB, IHC-P
- Reactivity: Human, Mouse, Rat
- Predicted Reactivity:
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Datasheet
Tech Support
IMAGES
Paraformaldehyde-fixed, paraffin embedded Rat brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with LMAN1 Monoclonal Antibody, Unconjugated (bsm-54753R) at 1:50 for 30 minutes at room temperature, DAB staining.
Paraformaldehyde-fixed, paraffin embedded Mouse testis; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with LMAN1 Monoclonal Antibody, Unconjugated (bsm-54753R) at 1:50 for 30 minutes at room temperature, DAB staining.
Paraformaldehyde-fixed, paraffin embedded Mouse kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with LMAN1 Monoclonal Antibody, Unconjugated (bsm-54753R) at 1:50 for 30 minutes at room temperature, DAB staining.
PRODUCT DETAILS
SPECIFICATIONS |
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|---|---|
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PRODUCT NAME |
LMAN1 Monoclonal Antibody |
|
CONJUGATION |
Unconjugated |
|
HOST |
Rabbit |
| SOURCE |
Synthetic peptide within N-terminal Human LMAN1. |
| IMMUNOGEN RANGE |
|
| CLONALITY |
Monoclonal |
| ISOTYPE |
IgG |
| CONCENTRATION |
1ug/ul |
| PURIFICATION |
Purified by Protein A. |
| STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
| STORAGE CONDITION |
Store at -20°C for 12 months.. |
TARGET |
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|---|---|
| GENE ID |
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| SUBCELLULAR LOCATION |
Endoplasmic reticulum membrane, Golgi apparatus membrane, ER-Golgi intermediate compartment membrane |
| SYNONYMS |
Endoplasmic reticulum golgi intermediate compartment protein 53 antibody, ER-Golgi intermediate compartment 53 kDa protein antibody, ERGIC-53 antibody, ERGIC53 antibody, ERGIC53 like protein antibody, F5F8D antibody, FMFD1 antibody, Gp58 antibody, Intracellular mannose specific lectin antibody, Intracellular mannose-specific lectin MR60 antibody, Lectin mannose binding 1 antibody, Lectin mannose-binding 1 antibody, Lman1 antibody, LMAN1 like protein antibody, LMAN1_HUMAN antibody, MCFD1 antibody, MR60 antibody, Protein ERGIC-53 antibody |
| BACKGROUND |
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq, Jul 2008] |
| APPLICATION DILUTION |
WB(1:300-1000), IHC-P(1:200-400) |