KIFAP3 Monoclonal Antibody
- Size: 100ul
- Application: WB, FCM, IHC-P, IF(ICC)
- Reactivity: Human, Mouse, Rat
- Predicted Reactivity:
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
KIFAP3 Monoclonal Antibody |
CONJUGATION |
Unconjugated |
HOST |
Rabbit |
SOURCE |
Synthetic Peptide within C-terminal human KIFAP3. |
IMMUNOGEN RANGE |
|
CLONALITY |
Monoclonal |
ISOTYPE |
IgG |
CONCENTRATION |
1ug/ul |
PURIFICATION |
Purified by Protein A. |
STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
STORAGE CONDITION |
Store at -20°C for 12 months.. |
TARGET |
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GENE ID |
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SUBCELLULAR LOCATION |
Cytoplasm, Nucleus, Endoplasmic reticulum, Golgi apparatus, Cytoskeleton, Plasma membrane |
SYNONYMS |
FLJ22818 antibody, KAP 3 antibody, KAP-3 antibody, KAP3 antibody, KIF3AP antibody, KIFA3_HUMAN antibody, Kifap3 antibody, Kinesin associated protein 3 antibody, Kinesin-associated protein 3 antibody, SMAP antibody, Smg GDS antibody, Smg GDS associated protein antibody, Smg GDS-associated protein antibody |
BACKGROUND |
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
APPLICATION DILUTION |
WB(1:300-1000), FCM(1:20-100), IHC-P(1:200-400), IF(ICC)(1:50-200) |