Frizzled 7 Polyclonal Antibody


Frizzled 7 Polyclonal Antibody

  • Size: 100ul
  • Application: WB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
  • Reactivity: Human, Mouse, Rat
  • Predicted Reactivity: Dog, Cow, Pig, Chicken, Guinea Pig

  • Datasheet      Tech Support


Catalog# bs-5125R

Size:100ul Datasheet


 SizePrice
 100ul ₹ 33990

Contact Us


IMAGES






PRODUCT DETAILS






SPECIFICATIONS

PRODUCT NAME

Frizzled 7 Polyclonal Antibody

CONJUGATION

Unconjugated

HOST

Rabbit

SOURCE

KLH conjugated synthetic peptide derived from human Frizzled 7

IMMUNOGEN RANGE

501-574/574

CLONALITY

Polyclonal

ISOTYPE

IgG

CONCENTRATION

1ug/ul

PURIFICATION

Purified by Protein A.

STORAGE BUFFER

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

STORAGE CONDITION

Store at -20°C for 12 months..


TARGET

GENE ID

8324

SUBCELLULAR LOCATION

Cell membrane

SYNONYMS

FzE3; Frizzled-7; Fz-7; hFz7; FZD7

BACKGROUND

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

APPLICATION DILUTION

WB(1:300-1000), ELISA(1:500-1000), FCM(1:20-100), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)












CITATION






  • Ye C et al. Overexpression of FZD7 is associated with poor survival in patients with colon cancer. Pathol Res Pract. 2019 May 27:152478., Pathol Res Pract.
    IHC | Human
  • Deng, Boya, et al. "MicroRNA-142-3p inhibits cell proliferation and invasion of cervical cancer cells by targeting FZD7." Tumor Biology (2015): 1-9., Tumor Biology
    WB | Human


Have you cited this product in a publication?
Let us know so we can reference it here.

Contact Us










We're here to help


Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.


Contact Tech Support







High Quality Guaranteed Product


Our products such as Elisa, Antibodies, Proteins, Peptides are covered by Biolinkk quality warranty and will work as described in datasheet, a free replacement or money back is guaranteed if does not perform according to datasheet.


Learn More