FRATAXIN (2G1) Monoclonal Antibody
- Size: 100ul
- Application: WB
- Reactivity: Human
- Predicted Reactivity:
-
Datasheet
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IMAGES
Lane 1: K562; Lane 2: Jurkat; Lane 3: Raji; Lane 4: DU145; Lane 5: mouse kidney; Lane 6: mouse liver; Lane 7: mouse heart lysates, probed with FRATAXIN (2G1) Monoclonal Antibody, Unconjugated (bsm-58001R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.
PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
FRATAXIN (2G1) Monoclonal Antibody |
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CONJUGATION |
Unconjugated |
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HOST |
Rabbit |
| SOURCE |
Full length recombinant human Frataxin protein |
| IMMUNOGEN RANGE |
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| CLONALITY |
Monoclonal |
| ISOTYPE |
IgG |
| CONCENTRATION |
Not Determined |
| PURIFICATION |
Purified by Protein A. |
| STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
| STORAGE CONDITION |
Store for 1 year at -20°C from date of shipment. Store for 1 year at -20°C from date of shipment. |
TARGET |
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| GENE ID |
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| SUBCELLULAR LOCATION |
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| SYNONYMS |
Frataxin, mitochondrial; FXN; Friedreich ataxia protein; FRDA; X25 |
| BACKGROUND |
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization; however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1. |
| APPLICATION DILUTION |
WB(1:300-1000) |