DOK1 Monoclonal Antibody
- Size: 100ul
- Application: WB
- Reactivity: Human, Rat
- Predicted Reactivity:
-
Datasheet
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
DOK1 Monoclonal Antibody |
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CONJUGATION |
Unconjugated |
|
HOST |
Rabbit |
| SOURCE |
Synthetic Peptide corresponding to Human DOK1. |
| IMMUNOGEN RANGE |
|
| CLONALITY |
Monoclonal |
| ISOTYPE |
IgG |
| CONCENTRATION |
1ug/ul |
| PURIFICATION |
Purified by Protein A. |
| STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
| STORAGE CONDITION |
Store at -20°C for 12 months.. |
TARGET |
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| GENE ID |
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| SUBCELLULAR LOCATION |
Cytoplasm, Nucleus, Perinuclear region |
| SYNONYMS |
Docking protein 1 62kD antibody, Docking protein 1 antibody, DOK 1 antibody, DOK1 antibody, DOK1_HUMAN antibody, Downstream of tyrosine kinase 1 antibody, p62(dok) antibody, P62DOK antibody, pp62 antibody |
| BACKGROUND |
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. |
| APPLICATION DILUTION |
WB(1:300-1000) |