Cytochrome C Polyclonal Antibody
- Size: 100ul
- Application: WB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), ICC
- Reactivity: Human, Mouse, Rat, Chicken, Rabbit
- Predicted Reactivity: Cow, Pig, Horse, Guinea Pig
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
Cytochrome C Polyclonal Antibody |
CONJUGATION |
Unconjugated |
HOST |
Rabbit |
SOURCE |
KLH conjugated synthetic peptide derived from human Cytochrome C |
IMMUNOGEN RANGE |
51-105/105 |
CLONALITY |
Polyclonal |
ISOTYPE |
IgG |
CONCENTRATION |
1ug/ul |
PURIFICATION |
Purified by Protein A. |
STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
STORAGE CONDITION |
Store at -20°C for 12 months.. |
TARGET |
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GENE ID |
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SUBCELLULAR LOCATION |
Cytoplasm, Cell membrane |
SYNONYMS |
CYC; HCS; THC4; Cytochrome c; CYCS |
BACKGROUND |
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. |
APPLICATION DILUTION |
WB(1:300-1000), ELISA(1:500-1000), FCM(1:20-100), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200), ICC(1:100-500) |