Bcl-2 Polyclonal Antibody
- Size: 100ul
- Application: WB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
- Reactivity: Human, Mouse, Rat, Bovine, Chicken, Rabbit, Bacteria
- Predicted Reactivity: Dog, Cow, Pig, Horse
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
Bcl-2 Polyclonal Antibody |
CONJUGATION |
Unconjugated |
HOST |
Rabbit |
SOURCE |
KLH conjugated synthetic peptide derived from rat Bcl-2 |
IMMUNOGEN RANGE |
101-160/236 |
CLONALITY |
Polyclonal |
ISOTYPE |
IgG |
CONCENTRATION |
1ug/ul |
PURIFICATION |
Purified by Protein A. |
STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
STORAGE CONDITION |
Store at -20°C for 12 months.. |
TARGET |
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GENE ID |
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SUBCELLULAR LOCATION |
Cytoplasm, Nucleus, Cell membrane |
SYNONYMS |
Bcl-2; Apoptosis regulator Bcl-2; Bcl2 |
BACKGROUND |
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). |
APPLICATION DILUTION |
WB(1:300-1000), ELISA(1:500-1000), FCM(1:20-100), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200) |