APLP2 Monoclonal Antibody
- Size: 100ul
- Application: WB, IHC-P
- Reactivity: Human, Rat
- Predicted Reactivity:
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
APLP2 Monoclonal Antibody |
CONJUGATION |
Unconjugated |
HOST |
Rabbit |
SOURCE |
Synthetic peptide within N-terminal Human APLP2. |
IMMUNOGEN RANGE |
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CLONALITY |
Monoclonal |
ISOTYPE |
IgG |
CONCENTRATION |
1ug/ul |
PURIFICATION |
Purified by Protein A. |
STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
STORAGE CONDITION |
Store at -20°C for 12 months.. |
TARGET |
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GENE ID |
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SUBCELLULAR LOCATION |
Nucleus, Cell membrane |
SYNONYMS |
amyloid beta (A4) precursor like protein 2 antibody, Amyloid like protein 2 antibody, Amyloid precursor protein homolog HSD 2 antibody, amyloid precursor protein homolog HSD2 antibody, Amyloid protein homolog antibody, Amyloid-like protein 2 antibody, APLP-2 antibody, Aplp2 antibody, APLP2_HUMAN antibody, APPH antibody, APPL2 antibody, CDEBP antibody, CDEI box binding protein antibody, CDEI box-binding protein antibody |
BACKGROUND |
APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24. May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. |
APPLICATION DILUTION |
WB(1:300-1000), IHC-P(1:200-400) |