Adrenomedullin Polyclonal Antibody
- Size: 100ul
- Application: ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
- Reactivity: Rat
- Predicted Reactivity: Human, Mouse, Dog, Cow, Horse
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
Adrenomedullin Polyclonal Antibody |
CONJUGATION |
Unconjugated |
HOST |
Rabbit |
SOURCE |
KLH conjugated synthetic peptide derived from human Adrenomedullin |
IMMUNOGEN RANGE |
122-140/185 |
CLONALITY |
Polyclonal |
ISOTYPE |
IgG |
CONCENTRATION |
1ug/ul |
PURIFICATION |
Purified by Protein A. |
STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
STORAGE CONDITION |
Store at -20°C for 12 months.. |
TARGET |
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GENE ID |
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SUBCELLULAR LOCATION |
Secreted |
SYNONYMS |
AM; PAMP; ADM; Adrenomedullin |
BACKGROUND |
AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels. |
APPLICATION DILUTION |
ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200) |