M7824 Biosimilar – Research Grade [ICH5095]
- Sizes: 0.1mg, 5mg, 10mg, 20mg, 50mg
- Category: ichorbio, Low endotoxin, fusion protein, bispecific
- Target: PD-L1&TGF-β
- Clone:
- Host: Humanized
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Datasheet
Tech Support
PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
M7824 Biosimilar - Research Grade [ICH5095] |
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SPECIES REACTIVITY |
Human |
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HOST |
Humanized |
| SPECIFICITY |
Bifunctional fusion protein composed of the extracellular domain of the TGF-βRII receptor fused to a human IgG1 monoclonal antibody blocking PD-L1 |
| PURIFICATION METHOD |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| ANTIGEN DISTRIBUTION |
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| IMMUNOGEN |
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| CONCENTRATION |
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| FORMULATION |
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free. |
| PURITY |
>95% by SDS-PAGE and HPLC |
| ENDOTOXIN |
≤ 0.75 EU/mg as determined by the LAL method |
| AGGRIGATION |
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| STORAGE CONDITION |
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
TARGET |
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| TARGET |
PD-L1&TGF-β |
| CLONE |
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| SYNONYMS |
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| BACKGROUND |
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| UNIPROT |
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| PATHOGEN TEST |
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| APPLICATIONS |
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| APPLICATION NOTES |
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| USAGE |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |