PRODUCT NAME

Anti-Mouse LAG-3 In Vivo Antibody - Ultra Low Endotoxin (C9B7W)

SPECIES REACTIVITY

Mouse

HOST

Rat

SPECIFICITY

Anti-LAG-3 In Vivo Antibody - Ultra Low Endotoxin (C9B7W) recognizes an epitope on Mouse LAG-3

PURIFICATION METHOD

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

ANTIGEN DISTRIBUTION

T-cells and NK cells

IMMUNOGEN

Murine CD223-Ig fusion protein

CONCENTRATION

FORMULATION

Sterile filtered & formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4 with no preservatives.

PURITY

>98% by SDS-PAGE and HPLC

ENDOTOXIN

≤ 0.75 EU/mg as determined by the LAL method

AGGRIGATION

Aggregation level ≤ 1%

STORAGE CONDITION

anti-LAG-3 In Vivo Antibody - Ultra Low Endotoxin (C9B7W) is stable when stored at 2-8°C.

TARGET

LAG3

CLONE

C9B7W

SYNONYMS

BACKGROUND

LAG-3, also known as CD223, is 70 kD type I transmembrane glycoprotein within the Ig superfamily. CD223, like CD4, binds MHC class II molecules, but with higher affinity than CD4. Clone C9B7W antibody has been reported to block the function of murine LAG-3 in vivo and in vitro.

UNIPROT

Q61790

PATHOGEN TEST

We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for:
Mycoplasma spp
Mycoplasma pulmonis
Pneumonia virus of mice
Kilham's rat virus
Toolan's H1 virus
Rat parvovirus
Lymphocytic choriomeningitis virus
Rat cytomegalovirus
Sendai virus
Rat coronavirus
Sialodacryoadenitis virus
Rat minute virus
Seoul virus
Mouse adenovirus
Reovirus 3
Rat theilovirus

APPLICATIONS

Western Blot, Blocking, Flow Cytometry, Immunoprecipitation, ELISA

APPLICATION NOTES

Each investigator should determine their own optimal working dilution for specific applications.

USAGE

Products are for research use only. Not for use in diagnostic or therapeutic procedures.