Anti-Mouse CD8a In Vivo Antibody – Ultra Low Endotoxin (2.43)
- Sizes: 5mg, 25mg, 50mg, 100mg,
- Category: ichorbio, Ultra Low Endotoxin, anti-mouse
- Target: CD8a
- Clone: 2.43
- Host: Rat
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
Anti-Mouse CD8a In Vivo Antibody - Ultra Low Endotoxin (2.43) |
SPECIES REACTIVITY |
Mouse |
HOST |
Rat |
SPECIFICITY |
Anti-CD8a In Vivo Antibody - Ultra Low Endotoxin (2.43) recognizes an epitope on Mouse CD8a |
PURIFICATION METHOD |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
ANTIGEN DISTRIBUTION |
CD8a (Ly 2.2) is present on the surface of most thymocytes and a subpopulation of mature T-lymphocytes which include most T suppressor/cytotoxic-cells. CD8 participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck. |
IMMUNOGEN |
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CONCENTRATION |
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FORMULATION |
This purified antibody is formulated with no carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl. |
PURITY |
>98% by SDS-PAGE and HPLC |
ENDOTOXIN |
≤ 0.75 EU/mg as determined by the LAL method |
AGGRIGATION |
Aggregation level ≤ 1% |
STORAGE CONDITION |
anti-CD8a In Vivo Antibody - Ultra Low Endotoxin (2.43) is stable when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 80°C. Avoid Repeated Freeze Thaw Cycles. |
TARGET |
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TARGET |
CD8a |
CLONE |
2.43 |
SYNONYMS |
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BACKGROUND |
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UNIPROT |
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PATHOGEN TEST |
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for: |
APPLICATIONS |
Immunoprecipitation, Western Blot, Flow Cytometry, Immunofluorescence, Functional Assays |
APPLICATION NOTES |
Functional Assay: In vivo Depletion: It has been reported that Balb/C mice may be injected intraperitoneally with 1.0 mg of Rat Anti-Mouse CD8a (Clone 2.43) antibody and allowed to rest for 24 hours for CD8+ T cell depletion. |
USAGE |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |