Anti-Mouse CD8a In Vivo Antibody – Ultra Low Endotoxin (53-6.7)
- Sizes: 5mg, 25mg, 50mg, 100mg,
- Category: ichorbio, Ultra Low Endotoxin, anti-mouse
- Target: CD8a
- Clone: 53-6.7
- Host: Rat
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
Anti-Mouse CD8a In Vivo Antibody - Ultra Low Endotoxin (53-6.7) |
SPECIES REACTIVITY |
Mouse |
HOST |
Rat |
SPECIFICITY |
Anti-CD8a In Vivo Antibody - Ultra Low Endotoxin (53-6.7) recognizes Lyt 2, lymphocyte differentiation antigen. The antibody precipitates 44 kDa and 33 kDa proteins and reacts with non-polymorphic determinant. |
PURIFICATION METHOD |
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ANTIGEN DISTRIBUTION |
Present on the surface of most thymocytes and a subpopulation of mature T-lymphocytes which include most T suppressor/cytotoxic cells. CD8 participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck. |
IMMUNOGEN |
Mouse thymus or spleen |
CONCENTRATION |
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FORMULATION |
0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
PURITY |
>98% by SDS-PAGE and HPLC |
ENDOTOXIN |
≤ 0.75 EU/mg as determined by the LAL method |
AGGRIGATION |
Aggregation level ≤ 1% |
STORAGE CONDITION |
anti-CD8a In Vivo Antibody - Ultra Low Endotoxin (53-6.7) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
TARGET |
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TARGET |
CD8a |
CLONE |
53-6.7 |
SYNONYMS |
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BACKGROUND |
CD8, a.k.a Lyt-2, Ly-2, or T8, consists of disulfide-linked A and β chains that form the A(CD8a)/β(CD8b) heterodimer and A/A homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 A/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR A/β T cells. |
UNIPROT |
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PATHOGEN TEST |
We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for: |
APPLICATIONS |
Immunoprecipitation, Western Blot, Flow Cytometry, CyTOF, IHC (Frozen) |
APPLICATION NOTES |
Immunoprecipitation: Rat Anti-Mouse CD8a (Clone 53-6.7) precipitates 44 kDa and 33 kDa proteins. |
USAGE |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |