Bulk anti-Human MHC Class I antibody (W6/32)
- Sizes: 5mg, 25mg, 50mg, 100mg,
- Category: ichorbio, Low Endotoxin, anti-human
- Target: MHC Class I
- Clone: W6/32
- Host: Mouse
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
Bulk anti-Human MHC Class I antibody (W6/32) |
SPECIES REACTIVITY |
Human |
HOST |
Mouse |
SPECIFICITY |
Anti-MHC Class I In Vivo Antibody - Low Endotoxin (W6/32) recognizes/reacts with major histocompatibility complex (MHC) class I, HLA-A, B, and C |
PURIFICATION METHOD |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
ANTIGEN DISTRIBUTION |
This HLA-A, B, C antigen is present on most nucleated cells of humans and old world monkeys. |
IMMUNOGEN |
Human tonsil cell membrane |
CONCENTRATION |
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FORMULATION |
No carrier proteins or preservatives in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl. |
PURITY |
>95% by SDS-PAGE and HPLC |
ENDOTOXIN |
≤ 1.0 EU/mg as determined by the LAL method |
AGGRIGATION |
Aggregation level ≤ 5% |
STORAGE CONDITION |
anti-MHC Class I In Vivo Antibody - Low Endotoxin (W6/32) is stable for at least six (6) weeks when stored sterile at 2-8°C. For long-term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. |
TARGET |
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TARGET |
MHC Class I |
CLONE |
W6/32 |
SYNONYMS |
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BACKGROUND |
MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in the presentation of antigens to CD8+ T cells and plays a central role in cell-mediated immune responses and tumor surveillance. |
UNIPROT |
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PATHOGEN TEST |
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APPLICATIONS |
Western Blot, Flow Cytometry, Immunoprecipitation, Functional Assays, IHC (Frozen) |
APPLICATION NOTES |
Each investigator should determine their own optimal working dilution for specific applications. |
USAGE |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |