Bulk anti-Human CD11b antibody (ICRF44)

Bulk anti-Human CD11b antibody (ICRF44)


Bulk anti-Human CD11b antibody (ICRF44)

  • Sizes: 5mg, 25mg, 50mg, 100mg,
  • Category: ichorbio, Low Endotoxin, anti-human
  • Target: CD11b
  • Clone: 44
  • Host: Mouse

  • Datasheet      Tech Support


Catalog# ICH1007

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PRODUCT DETAILS






SPECIFICATIONS

PRODUCT NAME

Bulk anti-Human CD11b antibody (ICRF44)

SPECIES REACTIVITY

Human

HOST

Mouse

SPECIFICITY

Anti-CD11b In Vivo Antibody - Low Endotoxin (44) recognizes Human CD11b. Anti-Human CD11b recognizes the alpha subunit of the CD11b/CD18 complex, an alpha/Beta heterodimeric surface glycoprotein on human leukocytes (Mr 165-170 kDa). The CD11b/CD18 antigen belongs to the B2 integrin family. Other names include Mac-1, Cr3, MO-1 and C3bi receptor. The CD11b molecule functions as a receptor for C3bi complement, clotting factor X, fibrinogen and ICAM-1.

PURIFICATION METHOD

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

ANTIGEN DISTRIBUTION

The CD11b antigen is expressed on approximately 30% of human peripheral blood lymphocytes, most natural killer lymphocytes, circulating monocytes, granulocytes, a subset of T-cells and subsets of macrophages.

IMMUNOGEN

Unknown

CONCENTRATION

FORMULATION

0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.

PURITY

>95% by SDS-PAGE and analyzed by silver stain.

ENDOTOXIN

≤ 1.0 EU/mg as determined by the LAL method

AGGRIGATION

Aggregation level ≤ 5%

STORAGE CONDITION

anti-CD11b In Vivo Antibody - Low Endotoxin (44) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.


TARGET

TARGET

CD11b

CLONE

44

SYNONYMS

BACKGROUND

Anti-CD11b may be used to study lymphocyte subsets in flow cytometry and in cell adhesion research (Mac-1). The antibody may be used to stain tissue sections which have been acetone fixed and frozen.

UNIPROT

P11215

PATHOGEN TEST

APPLICATIONS

Flow Cytometry, Western Blot, IHC (Frozen), Immunoprecipitation

APPLICATION NOTES

Each investigator should determine their own optimal working dilution for specific applications.

USAGE

Products are for research use only. Not for use in diagnostic or therapeutic procedures.












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