SLFN14 Polyclonal Antibody, Cy5 Conjugated
- Size: 100ul
- Application: IF(IHC-P)
- Reactivity: Human, Mouse, Rat
- Predicted Reactivity:
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
SLFN14 Polyclonal Antibody, Cy5 Conjugated |
CONJUGATION |
Cy5 |
HOST |
Rabbit |
SOURCE |
KLH conjugated synthetic peptide derived from human SLFN14 |
IMMUNOGEN RANGE |
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CLONALITY |
Polyclonal |
ISOTYPE |
IgG |
CONCENTRATION |
1ug/ul |
PURIFICATION |
Purified by Protein A. |
STORAGE BUFFER |
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
STORAGE CONDITION |
Store at 4°C for 12 months. |
TARGET |
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GENE ID |
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SUBCELLULAR LOCATION |
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SYNONYMS |
Schlafen family member 14; SLFN14; SLN14_HUMAN. |
BACKGROUND |
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12. |
APPLICATION DILUTION |
IF(IHC-P)(1:50-200) |