IRS1 (Tyr1179) Polyclonal Antibody
- Size: 100ul
- Application: WB, ELISA, FCM, IHC-P, IHC-F, IF(ICC), IF
- Reactivity: Human, Mouse, Rat
- Predicted Reactivity:
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
IRS1 (Tyr1179) Polyclonal Antibody |
CONJUGATION |
Unconjugated |
HOST |
Rabbit |
SOURCE |
KLH conjugated synthesised phosphopeptide derived from human IRS1 around the phosphorylation site of Ser1179. |
IMMUNOGEN RANGE |
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CLONALITY |
Polyclonal |
ISOTYPE |
IgG |
CONCENTRATION |
1ug/ul |
PURIFICATION |
Purified by Protein A. |
STORAGE BUFFER |
Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
STORAGE CONDITION |
Store at -20°C for 12 months.. |
TARGET |
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GENE ID |
|
SUBCELLULAR LOCATION |
Cell membrane |
SYNONYMS |
IRS1 (phospho S1179); p-IRS1 (phospho S1179); p-IRS1; IRS1(phospho-Ser1179); HIRS 1; HIRS1; Insulin Receptor Substrate 1; IRS-1; IRS 1; IRS1; OTTHUMP00000164234; IRS1_HUMAN. |
BACKGROUND |
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. |
APPLICATION DILUTION |
WB(1:300-1000), ELISA(1:500-1000), FCM(1:20-100), IHC-P(1:200-400), IHC-F(1:100-500), IF(ICC)(1:50-200), IF() |