Anti-Mouse TCR V gamma 2 In Vivo Antibody – Low Endotoxin (UC3-10A6)
- Sizes: 5mg, 25mg, 50mg, 100mg,
- Category: ichorbio, Low Endotoxin, anti-mouse
- Target: TCR V gamma 2
- Clone: UC3-10A6
- Host: Armenian Hamster
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PRODUCT DETAILS
SPECIFICATIONS |
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PRODUCT NAME |
Anti-Mouse TCR V gamma 2 In Vivo Antibody - Low Endotoxin (UC3-10A6) |
SPECIES REACTIVITY |
Mouse |
HOST |
Armenian Hamster |
SPECIFICITY |
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PURIFICATION METHOD |
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ANTIGEN DISTRIBUTION |
V gamma 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of gamma delta TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung. |
IMMUNOGEN |
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CONCENTRATION |
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FORMULATION |
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
PURITY |
>95% by SDS-PAGE and HPLC |
ENDOTOXIN |
<1.0 EU/mg as determined by the LAL method |
AGGRIGATION |
Aggregation level ≤ 5% |
STORAGE CONDITION |
anti-TCR V gamma 2 In Vivo Antibody - Low Endotoxin (UC3-10A6) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
TARGET |
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TARGET |
TCR V gamma 2 |
CLONE |
UC3-10A6 |
SYNONYMS |
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BACKGROUND |
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an alpha and beta chain in 95% of T cells, while 5% of T cells have TCRs consisting of gamma and delta chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules. |
UNIPROT |
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PATHOGEN TEST |
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APPLICATIONS |
Flow Cytometry, Immunoprecipitation, In vivo Depletion |
APPLICATION NOTES |
Flow Cytometry: It is recommended to use the indirect method for signal enhancement when enumerating cells expressing TCR. A suggested method would be to stain cells expressing TCR with Anti-Mouse TCR at ≤1.0 µg per 1.0 X 106 cells in a 100 µl total staining volume, followed by Goat Goat Anti-Armenian Hamster IgG (H&L)-R-phycoerythrin |
USAGE |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |