Description
Chenodeoxycholic acid (CDCA) is a hydrophobic primary bile acid that activates nuclear receptors involved in cholesterol metabolism. EC50 concentrations for activation of FXR (farnesoid X receptor) range from 13-34 μM. In cells, CDCA also binds to bile acid binding proteins (BABP) with a reported stoichiometery of 1:2.
Datasheet
SKU-Size | 2831-1G (Size: 1 g) 2831-5G (Size: 5 g) 2831-25G (Size: 25 g) |
Alternate Name | CDCA; Fluibil; Hekbilin; Anthropodeoxycholic Acid; Kebilis; Ulmenide |
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Appearance | White to off-white solid |
CAS # | 474-25-9 |
Molecular Formula | C₂₄H₄₀O₄ |
Molecular Weight | 392.57 |
Purity | ≥95% |
Solubility | EtOH (50 mg/ml) |
SMILES | CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C |
InChi | C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C |
InChi Key | RUDATBOHQWOJDD-BSWAIDMHSA-N |
PubChem CID | 10133 |
MDL Number | MFCD00064142 |
Handling | Hygroscopic |
Storage Conditions | -20°C |
Shipping Conditions | Gel Pack |
USAGE | For Research Use Only! Not For Use in Humans. |
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